A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux

Macroautophagy (autophagy) targets cytoplasmic cargoes to the lysosome for degradation. Like all vesicle trafficking, autophagy relies on phosphoinositide identity, concentration, and localization to execute multiple steps in this catabolic process. Here, we screen for phosphoinositide phosphatases...

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Detalles Bibliográficos
Autores principales: Allen, Elizabeth A., Amato, Clelia, Fortier, Tina M., Velentzas, Panagiotis, Wood, Will, Baehrecke, Eric H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594499/
https://www.ncbi.nlm.nih.gov/pubmed/32915229
http://dx.doi.org/10.1083/jcb.201909073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594499/
https://www.ncbi.nlm.nih.gov/pubmed/32915229
http://dx.doi.org/10.1083/jcb.201909073

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