PD-1 inhibitor inducing exosomal miR-34a-5p expression mediates the cross talk between cardiomyocyte and macrophage in immune checkpoint inhibitor–related cardiac dysfunction

BACKGROUND: Immune checkpoint inhibitors (ICIs) have been an important therapeutic advancement in the field of cancer medicine. Recent reports provided greater insights into the cardiovascular adverse events, which prohibited the use of ICIs. Cardiovascular adverse events occur in different forms, s...

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Detalles Bibliográficos
Autores principales: Xia, Wenzheng, Chen, Hanbin, Chen, Didi, Ye, Yijia, Xie, Congying, Hou, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594538/
https://www.ncbi.nlm.nih.gov/pubmed/33115945
http://dx.doi.org/10.1136/jitc-2020-001293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594538/
https://www.ncbi.nlm.nih.gov/pubmed/33115945
http://dx.doi.org/10.1136/jitc-2020-001293

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