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In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination

BACKGROUND: Pancreatic ductal adenocarcinoma (PDA) is an almost incurable tumor that is mostly resistant to chemotherapy (CT). Adaptive immune responses to tumor-associated antigens (TAA) have been reported, but immunotherapy (IT) clinical trials have not yet achieved any significant increase in sur...

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Detalles Bibliográficos
Autores principales: Mandili, Giorgia, Curcio, Claudia, Bulfamante, Sara, Follia, Laura, Ferrero, Giulio, Mazza, Emanuela, Principe, Moitza, Cordero, Francesca, Satolli, Maria Antonietta, Spadi, Rosella, Evangelista, Andrea, Giordano, Daniele, Viet, Duy, Cappello, Paola, Novelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594541/
https://www.ncbi.nlm.nih.gov/pubmed/33115943
http://dx.doi.org/10.1136/jitc-2020-001071