Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

BACKGROUND: Glioblastoma (GBM) consists of devastating neoplasms with high invasive capacity, which have been difficult to study in vitro in a human-derived model system. Therapeutic progress is also limited by cellular heterogeneity within and between tumors, among other factors such as therapy res...

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Detalles Bibliográficos
Autores principales: Krieger, Teresa G, Tirier, Stephan M, Park, Jeongbin, Jechow, Katharina, Eisemann, Tanja, Peterziel, Heike, Angel, Peter, Eils, Roland, Conrad, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594554/
https://www.ncbi.nlm.nih.gov/pubmed/32297954
http://dx.doi.org/10.1093/neuonc/noaa091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594554/
https://www.ncbi.nlm.nih.gov/pubmed/32297954
http://dx.doi.org/10.1093/neuonc/noaa091

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