Integration of Next-Generation Sequencing in Diagnosing and Minimal Residual Disease Detection in Patients With Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia

Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subtype of B cell ALL. It accounts for 20% of all B cell ALL cases and is similar to BCR-ABL1 in gene expression profile but lacks BCR-ABL fusion. It is highly heterogeneous and is characterized by genetic alterations that...

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Detalles Bibliográficos
Autores principales: Sherali, Nazleen, Hamadneh, Tariq, Aftab, Saba, Alfonso, Michael, Tsouklidis, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594661/
https://www.ncbi.nlm.nih.gov/pubmed/33133861
http://dx.doi.org/10.7759/cureus.10696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594661/
https://www.ncbi.nlm.nih.gov/pubmed/33133861
http://dx.doi.org/10.7759/cureus.10696

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