Insights Into Peptide Inhibition of Alpha-Synuclein Aggregation

α-Synuclein (aSyn) aggregation is an attractive target for therapeutic development for a range of neurodegenerative conditions, collectively termed synucleinopathies. Here, we probe the mechanism of action of a peptide 4554W, (KDGIVNGVKA), previously identified through intracellular library screenin...

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Detalles Bibliográficos
Autores principales: Torpey, James H., Meade, Richard M., Mistry, Ravina, Mason, Jody M., Madine, Jillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594713/
https://www.ncbi.nlm.nih.gov/pubmed/33177976
http://dx.doi.org/10.3389/fnins.2020.561462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594713/
https://www.ncbi.nlm.nih.gov/pubmed/33177976
http://dx.doi.org/10.3389/fnins.2020.561462

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