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Insights Into Peptide Inhibition of Alpha-Synuclein Aggregation

α-Synuclein (aSyn) aggregation is an attractive target for therapeutic development for a range of neurodegenerative conditions, collectively termed synucleinopathies. Here, we probe the mechanism of action of a peptide 4554W, (KDGIVNGVKA), previously identified through intracellular library screenin...

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Detalles Bibliográficos
Autores principales:	Torpey, James H., Meade, Richard M., Mistry, Ravina, Mason, Jody M., Madine, Jillian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594713/ https://www.ncbi.nlm.nih.gov/pubmed/33177976 http://dx.doi.org/10.3389/fnins.2020.561462

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