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Complete response with combined BRAF and MEK inhibition in BRAF mutated advanced low-grade serous ovarian carcinoma

More effective treatments are needed for low-grade serous ovarian carcinoma (LGSOC). Our patient, who suffers from metastatic LGSOC, had received all established treatments. Sequencing analysis revealed an activating BRAF mutation. Therefore, combined treatment with BRAF and MEK inhibitors, which is...

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Detalles Bibliográficos
Autores principales: Tholander, Bengt, Koliadi, Anthoula, Botling, Johan, Dahlstrand, Hanna, Von Heideman, Anne, Ahlström, Håkan, Öberg, Kjell, Ullenhag, Gustav J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594849/
https://www.ncbi.nlm.nih.gov/pubmed/33043759
http://dx.doi.org/10.1080/03009734.2020.1826612