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Distinctive alteration in the expression of autophagy genes in Drosophila models of amyloidopathy and tauopathy
BACKGROUND: Alzheimer’s disease (AD) is one the most common types of dementia. Plaques of amyloid beta and neurofibrillary tangles of tau are two major hallmarks of AD. Metabolism of these two proteins, in part, depends on autophagy pathways. Autophagy dysfunction and protein aggregation in AD may b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594860/ https://www.ncbi.nlm.nih.gov/pubmed/32657227 http://dx.doi.org/10.1080/03009734.2020.1785063 |