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Impact of Clinical Outcome Measures on Placebo Response Rates in Clinical Trials for Chronic Constipation: A Systematic Review and Meta-analysis

OBJECTIVES: Chronic constipation (CC) is a recurrent functional bowel disorder worldwide. The purpose of this study is to examine its pooled placebo response rate and compare placebo response level in randomized controlled trials (RCTs) with different endpoint assessments. METHODS: PubMed, Cochrane...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Liu, Xinghuang, Bai, Tao, Hou, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594913/
https://www.ncbi.nlm.nih.gov/pubmed/33259160
http://dx.doi.org/10.14309/ctg.0000000000000255