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A global antiB cell strategy combining obinutuzumab and daratumumab in severe pediatric nephrotic syndrome
BACKGROUND: Steroid-sensitive nephrotic syndrome (SSNS) is, in most patients, a chronic disease with 80% experiencing at least one relapse after first flare. B cell depletion using rituximab is effective in preventing relapse in steroid-dependent (SDNS) patients but fails to maintain long-term remis...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594934/ https://www.ncbi.nlm.nih.gov/pubmed/33118048 http://dx.doi.org/10.1007/s00467-020-04811-0 |