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A global antiB cell strategy combining obinutuzumab and daratumumab in severe pediatric nephrotic syndrome

BACKGROUND: Steroid-sensitive nephrotic syndrome (SSNS) is, in most patients, a chronic disease with 80% experiencing at least one relapse after first flare. B cell depletion using rituximab is effective in preventing relapse in steroid-dependent (SDNS) patients but fails to maintain long-term remis...

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Detalles Bibliográficos
Autores principales: Dossier, Claire, Prim, Benjamin, Moreau, Christelle, Kwon, Thérésa, Maisin, Anne, Nathanson, Sylvie, De Gennes, Christiane, Barsotti, Katia, Bourrassi, Abdelmajid, Hogan, Julien, Deschênes, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594934/
https://www.ncbi.nlm.nih.gov/pubmed/33118048
http://dx.doi.org/10.1007/s00467-020-04811-0