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Identification of SARS-CoV-2 entry inhibitors among already approved drugs

To discover effective drugs for COVID-19 treatment amongst already clinically approved drugs, we developed a high throughput screening assay for SARS-CoV-2 virus entry inhibitors using SARS2-S pseudotyped virus. An approved drug library of 1800 small molecular drugs was screened for SARS2 entry inhi...

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Detalles Bibliográficos
Autores principales: Yang, Li, Pei, Rong-juan, Li, Heng, Ma, Xin-na, Zhou, Yu, Zhu, Feng-hua, He, Pei-lan, Tang, Wei, Zhang, Ye-cheng, Xiong, Jin, Xiao, Shu-qi, Tong, Xian-kun, Zhang, Bo, Zuo, Jian-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594953/
https://www.ncbi.nlm.nih.gov/pubmed/33116249
http://dx.doi.org/10.1038/s41401-020-00556-6