Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells

Single-cell RNA sequencing studies on gene co-expression patterns could yield important regulatory and functional insights, but have so far been limited by the confounding effects of differentiation and cell cycle. We apply a tailored experimental design that eliminates these confounders, and report...

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Detalles Bibliográficos
Autores principales: Tarbier, Marcel, Mackowiak, Sebastian D., Frade, João, Catuara-Solarz, Silvina, Biryukova, Inna, Gelali, Eleni, Menéndez, Diego Bárcena, Zapata, Luis, Ossowski, Stephan, Bienko, Magda, Gallant, Caroline J., Friedländer, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595044/
https://www.ncbi.nlm.nih.gov/pubmed/33116115
http://dx.doi.org/10.1038/s41467-020-19011-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595044/
https://www.ncbi.nlm.nih.gov/pubmed/33116115
http://dx.doi.org/10.1038/s41467-020-19011-5

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