Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality

Abnormal levels of fibroblast growth factors (FGFs) and FGF receptors (FGFRs) have been detected in various neurological disorders. The potent impact of FGF-FGFR in multiple embryonic developmental processes makes it challenging to elucidate their roles in postmitotic neurons. Taking an alternative...

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Detalles Bibliográficos
Autores principales: Huang, Jui-Yen, Krebs, Bruna Baumgarten, Miskus, Marisha Lynn, Russell, May Lin, Duffy, Eamonn Patrick, Graf, Jason Michael, Lu, Hui-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595096/
https://www.ncbi.nlm.nih.gov/pubmed/33116259
http://dx.doi.org/10.1038/s41598-020-75537-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595096/
https://www.ncbi.nlm.nih.gov/pubmed/33116259
http://dx.doi.org/10.1038/s41598-020-75537-0

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