Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells

Memory B cells (MBCs) are long-lived and produce high-affinity, generally, class-switched antibodies. Here, we use a multiparameter approach involving CD27 to segregate naïve B cells (NBC), IgD(+) unswitched (unsw)MBCs and IgG(+) or IgA(+) class-switched (sw)MBCs from humans of different age, sex an...

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Detalles Bibliográficos
Autores principales: Moroney, Justin B., Vasudev, Anusha, Pertsemlidis, Alexander, Zan, Hong, Casali, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595102/
https://www.ncbi.nlm.nih.gov/pubmed/33116135
http://dx.doi.org/10.1038/s41467-020-19242-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595102/
https://www.ncbi.nlm.nih.gov/pubmed/33116135
http://dx.doi.org/10.1038/s41467-020-19242-6

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