Genome editing of CCR5 by CRISPR-Cas9 in Mauritian cynomolgus macaque embryos

The discovery that CCR5 serves as an R5-HIV-1 co-receptor, coupled with findings of protection from HIV infection in individuals lacking CCR5, led to the exploration of novel therapeutic strategies for HIV infection based on genome editing of CCR5. Advancing translation of CCR5-mutant-based cellular...

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Detalles Bibliográficos
Autores principales: Schmidt, Jenna Kropp, Strelchenko, Nick, Park, Mi Ae, Kim, Yun Hee, Mean, Katherine D., Schotzko, Michele L., Kang, Hyun Jun, Golos, Thaddeus G., Slukvin, Igor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595107/
https://www.ncbi.nlm.nih.gov/pubmed/33116147
http://dx.doi.org/10.1038/s41598-020-75295-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595107/
https://www.ncbi.nlm.nih.gov/pubmed/33116147
http://dx.doi.org/10.1038/s41598-020-75295-z

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