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Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer

Harmful effects of high fructose intake on health have been widely reported. Although fructose is known to promote cancer, little is known about the underlying mechanisms. Here, we found that fructose triggers breast cancer metastasis through the ketohexokinase-A signaling pathway. Molecular experim...

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Detalles Bibliográficos
Autores principales: Kim, Jiyoung, Kang, Jengmin, Kang, Ye-Lim, Woo, Jongmin, Kim, Youngsoo, Huh, June, Park, Jong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595112/
https://www.ncbi.nlm.nih.gov/pubmed/33116123
http://dx.doi.org/10.1038/s41467-020-19263-1