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Immune modulatory effects of oncogenic KRAS in cancer

Oncogenic KRAS mutations are the most frequent mutations in human cancer, but most difficult to target. While sustained proliferation caused by oncogenic KRAS-downstream signalling is a main driver of carcinogenesis, there is increasing evidence that it also mediates autocrine effects and crosstalk...

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Detalles Bibliográficos
Autores principales: Hamarsheh, Shaima’a, Groß, Olaf, Brummer, Tilman, Zeiser, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595113/
https://www.ncbi.nlm.nih.gov/pubmed/33116132
http://dx.doi.org/10.1038/s41467-020-19288-6