Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease

Iron accumulation in the substantia nigra is recognized as a hallmark of Parkinson’s disease (PD). Therefore, reducing accumulated iron and associated oxidative stress is considered a promising therapeutic strategy for PD. However, current iron chelators have poor membrane permeability and lack cell...

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Detalles Bibliográficos
Autores principales: Mu, Ming-Dao, Qian, Zhong-Ming, Yang, Sheng-Xi, Rong, Kang-Lin, Yung, Wing-Ho, Ke, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595123/
https://www.ncbi.nlm.nih.gov/pubmed/33116116
http://dx.doi.org/10.1038/s41419-020-03105-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595123/
https://www.ncbi.nlm.nih.gov/pubmed/33116116
http://dx.doi.org/10.1038/s41419-020-03105-5

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