Amorphous solid dispersions of enzalutamide and novel polysaccharide derivatives: investigation of relationships between polymer structure and performance

Amorphous solid dispersion (ASD) is a widely employed formulation technique for drugs with poor aqueous solubility. Polymers are integral components of ASDs, but mechanisms by which polymers lead to the generation and maintenance of supersaturated solutions, which enhance oral absorption in vivo, ar...

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Detalles Bibliográficos
Autores principales: Wilson, Venecia R., Lou, Xiaochun, Osterling, Donald J., Stolarik, DeAnne F., Jenkins, Gary J., Nichols, Brittany L. B., Dong, Yifan, Edgar, Kevin J., Zhang, Geoff G. Z., Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595150/
https://www.ncbi.nlm.nih.gov/pubmed/33116200
http://dx.doi.org/10.1038/s41598-020-75077-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595150/
https://www.ncbi.nlm.nih.gov/pubmed/33116200
http://dx.doi.org/10.1038/s41598-020-75077-7

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