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Interleukin-1 receptor-induced PGE(2) production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation

Scorpion envenomation is a leading cause of morbidity and mortality among accidents caused by venomous animals. Major clinical manifestations that precede death after scorpion envenomation include heart failure and pulmonary edema. Here, we demonstrate that cardiac dysfunction and fatal outcomes cau...

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Detalles Bibliográficos
Autores principales: Reis, Mouzarllem B., Rodrigues, Fernanda L., Lautherbach, Natalia, Kanashiro, Alexandre, Sorgi, Carlos A., Meirelles, Alyne F. G., Silva, Carlos A. A., Zoccal, Karina F., Souza, Camila O. S., Ramos, Simone G., Matsuno, Alessandra K., Rocha, Lenaldo B., Salgado, Helio C., Navegantes, Luiz C. C., Kettelhut, Ísis C., Cupo, Palmira, Gardinassi, Luiz G., Faccioli, Lúcia H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595177/
https://www.ncbi.nlm.nih.gov/pubmed/33116136
http://dx.doi.org/10.1038/s41467-020-19232-8