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A compound combination screening approach with potential to identify new treatment options for paediatric acute myeloid leukaemia

Paediatric acute myeloid leukaemia (AML) is a heterogeneous disease characterised by genetics and morphology. The introduction of intensive chemotherapy treatments together with patient stratification and supportive therapy has resulted in a moderate improvement in patient prognosis. However, overal...

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Detalles Bibliográficos
Autores principales: Lappin, Katrina M., Davis, Lindsay, Matchett, Kyle B., Ge, Yubin, Mills, Ken I., Blayney, Jaine K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595190/
https://www.ncbi.nlm.nih.gov/pubmed/33116257
http://dx.doi.org/10.1038/s41598-020-75453-3