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G82S RAGE polymorphism influences amyloid-RAGE interactions relevant in Alzheimer’s disease pathology
Receptor for advanced glycation end products (RAGE) has been implicated in the pathophysiology of Alzheimers disease(AD) due to its ability to bind amyloid-beta (Aβ42) and mediate inflammatory response. G82S RAGE polymorphism is associated with AD but the molecular mechanism for this association is...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595441/ https://www.ncbi.nlm.nih.gov/pubmed/33119615 http://dx.doi.org/10.1371/journal.pone.0225487 |