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G82S RAGE polymorphism influences amyloid-RAGE interactions relevant in Alzheimer’s disease pathology

Receptor for advanced glycation end products (RAGE) has been implicated in the pathophysiology of Alzheimers disease(AD) due to its ability to bind amyloid-beta (Aβ42) and mediate inflammatory response. G82S RAGE polymorphism is associated with AD but the molecular mechanism for this association is...

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Detalles Bibliográficos
Autores principales:	C, Rani Cathrine., Lukose, Bincy, Rani, P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595441/ https://www.ncbi.nlm.nih.gov/pubmed/33119615 http://dx.doi.org/10.1371/journal.pone.0225487

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