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Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34

Cancer immunotherapy based on Immune checkpoint blockade (ICB) is a promising strategy to treat patients with advanced highly aggressive therapy-resistant tumors. Unfortunately, the clinical reality is that only a small number of patients benefit from the remarkable clinical remissions achieved by I...

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Detalles Bibliográficos
Autores principales: Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595609/
https://www.ncbi.nlm.nih.gov/pubmed/32892693
http://dx.doi.org/10.1080/15548627.2020.1815439