Cargando…
Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34
Cancer immunotherapy based on Immune checkpoint blockade (ICB) is a promising strategy to treat patients with advanced highly aggressive therapy-resistant tumors. Unfortunately, the clinical reality is that only a small number of patients benefit from the remarkable clinical remissions achieved by I...
Autores principales: | Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595609/ https://www.ncbi.nlm.nih.gov/pubmed/32892693 http://dx.doi.org/10.1080/15548627.2020.1815439 |
Ejemplares similares
-
Firing up the cold tumors by targeting Vps34
por: Janji, Bassam, et al.
Publicado: (2020) -
Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy
por: Noman, Muhammad Zaeem, et al.
Publicado: (2020) -
LC3s hire membrane breakers to attack viral shelters
por: Biering, Scott B., et al.
Publicado: (2017) -
microRNA 30A promotes autophagy in response to cancer therapy
por: Yu, Yan, et al.
Publicado: (2012) -
Viral subversion of autophagy impairs oncogene-induced senescence
por: Leidal, Andrew M., et al.
Publicado: (2012)