The function of peroxisome proliferator-activated receptors PPAR-γ and PPAR-δ in Mycobacterium leprae-induced foam cell formation in host macrophages

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). In lepromatous leprosy (LL), skin macrophages, harboring extensive bacterial multiplication, gain a distinctive foamy appearance due to increased intracellular lipid load. To determine the mechanism by which M. lepra...

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Detalles Bibliográficos
Autores principales: Luo, Yuqian, Tanigawa, Kazunari, Kawashima, Akira, Ishido, Yuko, Ishii, Norihisa, Suzuki, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595635/
https://www.ncbi.nlm.nih.gov/pubmed/33075048
http://dx.doi.org/10.1371/journal.pntd.0008850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595635/
https://www.ncbi.nlm.nih.gov/pubmed/33075048
http://dx.doi.org/10.1371/journal.pntd.0008850

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