Cargando…

Honokiol protects against epidural fibrosis by inhibiting fibroblast proliferation and extracellular matrix overproduction in rats post-laminectomy

Epidural fibrosis (EF)-induced failed back surgery syndrome (FBSS) in patients post-laminectomy remains a medical challenge. Although the scarring mechanisms remain unclear, the majority of aetiological studies have reported fibroblast dysfunction. Honokiol, the major bioactive constituent of the ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Daoliang, Zeng, Weimin, Han, Xuyao, Qian, Tianchen, Sun, Jingyu, Qi, Fangzhou, Liu, Chen, Wang, Quan, Jin, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595651/
https://www.ncbi.nlm.nih.gov/pubmed/33125121
http://dx.doi.org/10.3892/ijmm.2020.4765