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Honokiol protects against epidural fibrosis by inhibiting fibroblast proliferation and extracellular matrix overproduction in rats post-laminectomy

Epidural fibrosis (EF)-induced failed back surgery syndrome (FBSS) in patients post-laminectomy remains a medical challenge. Although the scarring mechanisms remain unclear, the majority of aetiological studies have reported fibroblast dysfunction. Honokiol, the major bioactive constituent of the ma...

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Detalles Bibliográficos
Autores principales: Xu, Daoliang, Zeng, Weimin, Han, Xuyao, Qian, Tianchen, Sun, Jingyu, Qi, Fangzhou, Liu, Chen, Wang, Quan, Jin, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595651/
https://www.ncbi.nlm.nih.gov/pubmed/33125121
http://dx.doi.org/10.3892/ijmm.2020.4765

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