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Antihypertensive activity of oleanolic acid is mediated via downregulation of secretory phospholipase A(2) and fatty acid synthase in spontaneously hypertensive rats

Oleanolic acid (OA) is reported to possess antihypertensive activity via the regulation of lipid metabolism; however, the mechanisms underlying lipid regulation by OA are yet to be fully elucidated. The aim of the present study was to evaluate the mechanisms via which OA regulates lipid metabolism i...

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Detalles Bibliográficos
Autores principales: Zhang, Shiming, Liu, Yuecheng, Wang, Xiaoming, Tian, Zhenhua, Qi, Dongmei, Li, Yunlun, Jiang, Haiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595669/
https://www.ncbi.nlm.nih.gov/pubmed/33125128
http://dx.doi.org/10.3892/ijmm.2020.4744