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CTLA‐4 and HLA‐DQ are key molecules in the regulation of mDC‐mediated cellular immunity by Tregs in severe aplastic anemia

BACKGROUND: Regulatory T cells (Tregs) inhibit the activation of cluster of differentiation (CD) 4(+), CD8(+)T cells and the antigen‐presenting process of antigen‐presenting cells, and may play an important role in acquired severe aplastic anemia (SAA). METHODS: Flow cytometry was used to measure CD...

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Detalles Bibliográficos
Autores principales: Liu, Bingnan, Shao, Yuanyuan, Liang, Xiaowei, Lu, Dan, Yan, Li, Churov, Alexey, Fu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595925/
https://www.ncbi.nlm.nih.gov/pubmed/32621335
http://dx.doi.org/10.1002/jcla.23443