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Improved production of Humira antibody in the genetically engineered Escherichia coli SHuffle, by co-expression of human PDI-GPx7 fusions

ABSTRACT: Microbial production of antibodies offers the promise of cheap, fast, and efficient production of antibodies at an industrial scale. Limiting this capacity in prokaryotes is the absence of the post-translational machinery, present in dedicated antibody producing eukaryotic cell lines, such...

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Detalles Bibliográficos
Autores principales: Lénon, Marine, Ke, Na, Szady, Cecily, Sakhtah, Hassan, Ren, Guoping, Manta, Bruno, Causey, Bryce, Berkmen, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595990/
https://www.ncbi.nlm.nih.gov/pubmed/32997203
http://dx.doi.org/10.1007/s00253-020-10920-5