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IFI16 promotes human embryonic stem cell trilineage specification through interaction with p53

Transcriptional regulation plays an essential role in the self-renewal and differentiation of human embryonic stem cells (hESCs). However, how external signals disrupt the self-renewal regulatory network and further drive hESC differentiation remains largely unknown. Here, we found the immune regula...

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Detalles Bibliográficos
Autores principales: He, Qian, Wu, Zubiao, Yang, Wei, Jiang, Doukou, Hu, Chaofeng, Yang, Xiaofei, Li, Ning, Li, Furong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596047/
https://www.ncbi.nlm.nih.gov/pubmed/33298947
http://dx.doi.org/10.1038/s41536-020-00104-0