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Subcellular localization of HMGB1 in colorectal cancer impacts on tumor grade and survival prognosis

The high-mobility group box-1 (HMGB1) protein is implicated in the development of various cancers and their proliferation. According to its function, HMGB1 shuttles between the cell nucleus and cytoplasm, assisting with nucleosome stabilization and gene transcription, or localizing in the cell membr...

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Detalles Bibliográficos
Autores principales: Wang, Chao-Qun, Huang, Bi-Fei, Wang, Yan, Tang, Chih-Hsin, Jin, Hong-Chuan, Shao, Feng, Shao, Jun-Kang, Wang, Qian, Zeng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596050/
https://www.ncbi.nlm.nih.gov/pubmed/33122771
http://dx.doi.org/10.1038/s41598-020-75783-2