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Subcellular localization of HMGB1 in colorectal cancer impacts on tumor grade and survival prognosis
The high-mobility group box-1 (HMGB1) protein is implicated in the development of various cancers and their proliferation. According to its function, HMGB1 shuttles between the cell nucleus and cytoplasm, assisting with nucleosome stabilization and gene transcription, or localizing in the cell membr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596050/ https://www.ncbi.nlm.nih.gov/pubmed/33122771 http://dx.doi.org/10.1038/s41598-020-75783-2 |