The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors

Although numerous pathogenic mutations have been identified in various subunits of N-methyl-D-aspartate receptors (NMDARs), ionotropic glutamate receptors that are central to glutamatergic neurotransmission, the functional effects of these mutations are often unknown. Here, we combined in silico mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Skrenkova, Kristyna, Song, Jae-man, Kortus, Stepan, Kolcheva, Marharyta, Netolicky, Jakub, Hemelikova, Katarina, Kaniakova, Martina, Krausova, Barbora Hrcka, Kucera, Tomas, Korabecny, Jan, Suh, Young Ho, Horak, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596085/
https://www.ncbi.nlm.nih.gov/pubmed/33122756
http://dx.doi.org/10.1038/s41598-020-75646-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596085/
https://www.ncbi.nlm.nih.gov/pubmed/33122756
http://dx.doi.org/10.1038/s41598-020-75646-w

Ejemplares similares