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Beyond just a tight fortress: contribution of stroma to epithelial-mesenchymal transition in pancreatic cancer
Novel effective treatment is direly needed for patients with pancreatic ductal adenocarcinoma (PDAC). Therapeutics that target the driver mutations, especially the KRAS oncoprotein and its effector cascades, have been ineffective. It is increasing clear that the extensive fibro-inflammatory stroma (...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596088/ https://www.ncbi.nlm.nih.gov/pubmed/33122631 http://dx.doi.org/10.1038/s41392-020-00341-1 |