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Automated synthesis and preliminary evaluation of [(18)F]FDPA for cardiac inflammation imaging in rats after myocardial infarction

A translocator protein 18 kDa targeted radiotracer, N,N-diethyl-2-(2-(4-[(18)F]fluorophenyl)-5,7-dimethylpyrazolo[1,5-a] pyrimidin-3-yl) acetamide ([(18)F]FDPA), was automated synthetized and evaluated for cardiac inflammation imaging. Various reaction conditions for an automated synthesis were syst...

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Detalles Bibliográficos
Autores principales: Mou, Tiantian, Tian, Jing, Tian, Yi, Yun, Mingkai, Li, Junqi, Dong, Wei, Lu, Xia, Zhu, Ziwei, Mi, Hongzhi, Zhang, Xiaoli, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596090/
https://www.ncbi.nlm.nih.gov/pubmed/33122775
http://dx.doi.org/10.1038/s41598-020-75705-2