Oxidation of ethidium-based probes by biological radicals: mechanism, kinetics and implications for the detection of superoxide

Hydroethidine (HE) and hydropropidine ([Formula: see text] ) are fluorogenic probes used for the detection of the intra- and extracellular superoxide radical anion ([Formula: see text] ). In this study, we provide evidence that HE and [Formula: see text] react rapidly with the biologically relevant...

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Detalles Bibliográficos
Autores principales: Michalski, Radosław, Thiebaut, David, Michałowski, Bartosz, Ayhan, Mehmet M., Hardy, Micael, Ouari, Olivier, Rostkowski, Michał, Smulik-Izydorczyk, Renata, Artelska, Angelika, Marcinek, Andrzej, Zielonka, Jacek, Kalyanaraman, Balaraman, Sikora, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596101/
https://www.ncbi.nlm.nih.gov/pubmed/33122809
http://dx.doi.org/10.1038/s41598-020-75373-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596101/
https://www.ncbi.nlm.nih.gov/pubmed/33122809
http://dx.doi.org/10.1038/s41598-020-75373-2

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