Degradation and Transmission of Tau by Autophagic-Endolysosomal Networks and Potential Therapeutic Targets for Tauopathy

Tauopathies are a class of neurodegenerative diseases, including Alzheimer’s disease (AD), Frontotemporal Dementia (FTD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), and many others where microtubule-associated protein tau (MAPT or tau) is hyperphosphorylated and aggregate...

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Detalles Bibliográficos
Autores principales: Jiang, Shanya, Bhaskar, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596180/
https://www.ncbi.nlm.nih.gov/pubmed/33177989
http://dx.doi.org/10.3389/fnmol.2020.586731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596180/
https://www.ncbi.nlm.nih.gov/pubmed/33177989
http://dx.doi.org/10.3389/fnmol.2020.586731

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