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Engineering Three-Dimensional Tumor Models to Study Glioma Cancer Stem Cells and Tumor Microenvironment

Glioblastoma (GBM) is the most common and devastating primary brain tumor, leading to a uniform fatality after diagnosis. A major difficulty in eradicating GBM is the presence of microscopic residual infiltrating disease remaining after multimodality treatment. Glioma cancer stem cells (CSCs) have b...

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Detalles Bibliográficos
Autores principales: Ruiz-Garcia, Henry, Alvarado-Estrada, Keila, Schiapparelli, Paula, Quinones-Hinojosa, Alfredo, Trifiletti, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596188/
https://www.ncbi.nlm.nih.gov/pubmed/33177991
http://dx.doi.org/10.3389/fncel.2020.558381