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Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes

Combining experimental and simulation strategies to facilitate the design and operation of nucleic acid hybridization probes are highly important to both fundamental DNA nanotechnology and diverse biological/biomedical applications. Herein, we introduce a DNA equalizer gate (DEG) approach, a class o...

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Detalles Bibliográficos
Autores principales: Wang, Guan A., Xie, Xiaoyu, Mansour, Hayam, Chen, Fangfang, Matamoros, Gabriela, Sanchez, Ana L., Fan, Chunhai, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596233/
https://www.ncbi.nlm.nih.gov/pubmed/33122648
http://dx.doi.org/10.1038/s41467-020-19269-9