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Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
Combining experimental and simulation strategies to facilitate the design and operation of nucleic acid hybridization probes are highly important to both fundamental DNA nanotechnology and diverse biological/biomedical applications. Herein, we introduce a DNA equalizer gate (DEG) approach, a class o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596233/ https://www.ncbi.nlm.nih.gov/pubmed/33122648 http://dx.doi.org/10.1038/s41467-020-19269-9 |