Microglial response to experimental periodontitis in a murine model of Alzheimer’s disease

Periodontal disease (PD) has been suggested to be a risk factor for Alzheimer’s disease (AD). We tested the impact of ligature-induced PD on 5xFAD mice and WT littermates. At baseline, 5xFAD mice presented significant alveolar bone loss compared to WT mice. After the induction of PD, both WT and 5xF...

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Detalles Bibliográficos
Autores principales: Kantarci, Alpdogan, Tognoni, Christina M., Yaghmoor, Wael, Marghalani, Amin, Stephens, Danielle, Ahn, Jae-Yong, Carreras, Isabel, Dedeoglu, Alpaslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596239/
https://www.ncbi.nlm.nih.gov/pubmed/33122702
http://dx.doi.org/10.1038/s41598-020-75517-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596239/
https://www.ncbi.nlm.nih.gov/pubmed/33122702
http://dx.doi.org/10.1038/s41598-020-75517-4

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