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Microglial response to experimental periodontitis in a murine model of Alzheimer’s disease

Periodontal disease (PD) has been suggested to be a risk factor for Alzheimer’s disease (AD). We tested the impact of ligature-induced PD on 5xFAD mice and WT littermates. At baseline, 5xFAD mice presented significant alveolar bone loss compared to WT mice. After the induction of PD, both WT and 5xF...

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Detalles Bibliográficos
Autores principales:	Kantarci, Alpdogan, Tognoni, Christina M., Yaghmoor, Wael, Marghalani, Amin, Stephens, Danielle, Ahn, Jae-Yong, Carreras, Isabel, Dedeoglu, Alpaslan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596239/ https://www.ncbi.nlm.nih.gov/pubmed/33122702 http://dx.doi.org/10.1038/s41598-020-75517-4

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