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Hepcidin Decreases Rotenone-Induced α-Synuclein Accumulation via Autophagy in SH-SY5Y Cells

Parkinson’s disease (PD) is a neurodegenerative disorder, and the hallmarks of this disease include iron deposition and α-synuclein (α-syn) aggregation. Hepcidin could reduce iron in the central and peripheral nervous systems. Here, we hypothesized that hepcidin could further decrease α-syn accumula...

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Detalles Bibliográficos
Autores principales: Li, Meiqi, Hu, Jianan, Yuan, Xiaoyu, Shen, Lihua, Zhu, Li, Luo, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596286/
https://www.ncbi.nlm.nih.gov/pubmed/33177988
http://dx.doi.org/10.3389/fnmol.2020.560891