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Dietary Protein and Amino Acid Deficiency Inhibit Pancreatic Digestive Enzyme mRNA Translation by Multiple Mechanisms

BACKGROUND & AIMS: Chronic amino acid (AA) deficiency, as in kwashiorkor, reduces the size of the pancreas through an effect on mammalian target of rapamycin complex 1 (mTORC1). Because of the physiological importance of AAs and their role as a substrate, a stimulant of mTORC1, and protein synth...

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Detalles Bibliográficos
Autores principales: Sans, Maria Dolors, Crozier, Stephen J., Vogel, Nancy L., D’Alecy, Louis G., Williams, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596297/
https://www.ncbi.nlm.nih.gov/pubmed/32735995
http://dx.doi.org/10.1016/j.jcmgh.2020.07.008