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Dietary Protein and Amino Acid Deficiency Inhibit Pancreatic Digestive Enzyme mRNA Translation by Multiple Mechanisms
BACKGROUND & AIMS: Chronic amino acid (AA) deficiency, as in kwashiorkor, reduces the size of the pancreas through an effect on mammalian target of rapamycin complex 1 (mTORC1). Because of the physiological importance of AAs and their role as a substrate, a stimulant of mTORC1, and protein synth...
Autores principales: | Sans, Maria Dolors, Crozier, Stephen J., Vogel, Nancy L., D’Alecy, Louis G., Williams, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596297/ https://www.ncbi.nlm.nih.gov/pubmed/32735995 http://dx.doi.org/10.1016/j.jcmgh.2020.07.008 |
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