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CD26 upregulates proliferation and invasion in keloid fibroblasts through an IGF-1-induced PI3K/AKT/mTOR pathway

BACKGROUND: Keloid is a fibrotic dermal disease characterized by an abnormal increase in fibroblast proliferation and invasion. These pathological behaviours may be related to the heterogeneity of keloid fibroblasts (KFs); however, because of a lack of effective biomarkers for KFs it is difficult to...

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Detalles Bibliográficos
Autores principales: Xin, Yu, Min, Peiru, Xu, Heng, Zhang, Zheng, Zhang, Yan, Zhang, Yixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596300/
https://www.ncbi.nlm.nih.gov/pubmed/33150188
http://dx.doi.org/10.1093/burnst/tkaa025