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The Novel Omega-6 Fatty Acid Docosapentaenoic Acid Positively Modulates Brain Innate Immune Response for Resolving Neuroinflammation at Early and Late Stages of Humanized APOE-Based Alzheimer's Disease Models

Neuroinflammation plays a crucial role in the development and progression of Alzheimer's disease (AD), in which activated microglia are found to be associated with neurodegeneration. However, there is limited evidence showing how neuroinflammation and activated microglia are directly linked to...

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Detalles Bibliográficos
Autores principales: Ma, Qiu-Lan, Zhu, Cansheng, Morselli, Marco, Su, Trent, Pelligrini, Matteo, Lu, Zhengqi, Jones, Mychica, Denver, Paul, Castro, Daniel, Gu, Xuelin, Relampagos, Frances, Caoili, Kaitlin, Teter, Bruce, Frautschy, Sally A., Cole, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596305/
https://www.ncbi.nlm.nih.gov/pubmed/33178186
http://dx.doi.org/10.3389/fimmu.2020.558036