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Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma

Aryl hydrocarbon receptor (AhR) provides a deeper insight into the pathogenesis of cutaneous squamous cell carcinoma (cSCC). AhR ligands, such as 6-formylindolo[3,2-b] carbazole (FICZ), and 7,12-Dimethylbenz[a]anthracene (DMBA), constitute major substrates for the cytochrome P450 (CYP) family, and i...

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Detalles Bibliográficos
Autores principales: Sato, Yota, Fujimura, Taku, Hidaka, Takanori, Lyu, Chunbing, Tanita, Kayo, Matsushita, Shigeto, Yamamoto, Masayuki, Aiba, Setsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596320/
https://www.ncbi.nlm.nih.gov/pubmed/33178182
http://dx.doi.org/10.3389/fimmu.2020.534323