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In vivo cardiac pacemaker function of differentiated human mesenchymal stem cells from adipose tissue transplanted into porcine hearts

BACKGROUND: Mesenchymal stem cells (MSC) modified by gene transfer to express cardiac pacemaker channels such as HCN2 or HCN4 were shown to elicit pacemaker function after intracardiac transplantation in experimental animal models. Human MSC derived from adipose tissue (haMSC) differentiate into cel...

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Detalles Bibliográficos
Autores principales: Darche, Fabrice F, Rivinius, Rasmus, Rahm, Ann-Kathrin, Köllensperger, Eva, Leimer, Uwe, Germann, Günter, Reiss, Miriam, Koenen, Michael, Katus, Hugo A, Thomas, Dierk, Schweizer, Patrick A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596441/
https://www.ncbi.nlm.nih.gov/pubmed/33178397
http://dx.doi.org/10.4252/wjsc.v12.i10.1133